This brief provides an overview of agriculture in urbanizing parts of the United States. We refer to these areas as the “rural-urban interface” (RUI1) given that they include both urban and rural land. We describe some of the broad trends and developments in commercial farming in these areas, and show how commercial farming is still quite vibrant and dynamic in many RUI counties. Our research suggests that innovative local, state, and national policies can have an important influence on the future of RUI agriculture.